International Journal of Pharma and Bio Sciences
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editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 2 Issue 1
2011 (January - March)
Synthesis,characterisation and antibacterial,antifungal activities of schiff bases of 4 - (2- aminphenyl)morpholines.
A Series of Schiff's bases of 4(2-amino phenyl) morpholines (1-V) were synthesized compounds were confirmed by IR, 1HNMR and MASS spectrum. All the newly synthesized compounds have been screened for their in vitro antibacterial activities against S.aureus , S. epidermis, B. cereus, B. subtilis, Ps. aureus, Kl. pneumonia and E. coli and antifungal activities against A. niger and C. albicans. Their minimal inhibitory concentration (MIC) values ranged between 1-10 µg/ml. The screening data indicates that the compounds I to V have promising anti-bacterial activity and antifungal activity by disc diffusion method by measuring the zone of inhibition and the results were compared to standard drugs ciprofloxacin and ketoconazole respectively. lessThan br / greaterThan
Gnana Ruba Priya,Panneerselvam,Karikalan
Synthesis, morpholines derivatives, Schiff base, Anti-bacterial activity
267-272