International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 1 Issue 3
2010 (July - September)
Synthesis and Antimicrobial Evaluation of Novel Schiff Bases Analogue of 3-(4-Amino) Phenylimino) 5-Fluoroindolin-2-One
The synthesis and the in vitro evaluation of antibacterial activity of new schiff bases analogues of 3-(4-Amino) Phenylimino) 5- substituted indolin-2-One are reported. The newly synthesized compounds were characterized by IR, 1H NMR and Mass spectral studies. Representative compounds were screened for antibacterial (Staphylococcus aureus ATCC-9144, Staphylococcus epidermidis ATCC-155, Micrococcus luteus ATCC-4698, Bacillus cereus ATCC-11778, Escherichia coli ATCC-25922, Pseudomonas aeruginosa ATCC-2853, and Klebsiella pneumoniae ATCC-11298) and antifungal (Aspergillus niger ATCC-9029 and Aspergillus fumigatus ATCC-46645) activities by paper disc diffusion technique. The minimum inhibitory concentrations (MICs) of the compounds were also determined by agar streak dilution method. lessThan br / greaterThan
Nirmal R., Ajay Babu C.H., Prasad Rao M.
Schiff base, 3-(4-Amino) Phenylimino) 5- substituted indolin-2-One , Anitmicrobial study
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