International Journal of Pharma and Bio Sciences
ijpbs.net
editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 5 Issue 3
2014 (July- September)
AN ASSESSMENT OF THE TARGET ORGAN DAMAGE AMONG PATIENTS OF RESISTANT HYPERTENSION- A CROSS SECTIONAL STUDY
This study aimed to assess the distribution of target organ damage among the patients with Resistant hypertension. A Cross sectional study of a cohort of patients with resistant hypertension as defined by WHO-ISH Criteria was conducted. Patients' characteristics, history, physical examination and relevant investigations were done. Target organ damages was diagnosed and graded by standard criteria. Binomial test, chi square test were applied and the p value was computed to know the statistical significance of results obtained. A total of 233 patients were included in the study. 84.12% of the study population (196 patients) had evidence of cardiovascular system involvement, 42.92% had renal system involvement, and 27 patients (11.58%) had central nervous system involvement. The Least number of patients had evidence of ophthalmic (8.58%) and respiratory system (0.86%). This percentage doesn't add up to 100 as patients had multiple system involvement. Out of total target organs/system damaged in our study the most commonly effected system was cardiovascular system (56.81% of all target organs damaged) followed by renal (28.98%). Maximum number of patients (83) had left ventricular hypertrophy as evidenced by ECG or 2 D ECHO followed by 73 patients who had ischemic heart disease. Central nervous system involvement (7.83%) was seen in 27 patients.In conclusion , Heart and kidneys is the common target organs to be damaged in patients with resistant hypertension
SHAYLIKA CHAUHAN AND ARUNDHATIKANBUR
Resistant Hypertension, target organ damage
320-332