International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 4 Issue 4
2013 (October - December)
MOLECULAR CHARACTERIZATION, PHYTOCHEMICAL AND DOCKING STUDIES OF MOSQUITO REPELLENT COMPOUNDS IN OCIMUMBASILICUM LINN.VAR. PILOSUM (WILLD.) - BENTH.
Many species of lessThan i greaterThan Ocimum lessThan /i greaterThan reported to exhibit insecticidal and insect repellent properties. In the present investigation, molecular characterization of lessThan i greaterThan Ocimum basilicum Linn. var. pilosum (willd)- Benth lessThan /i greaterThan was carried out with EST SSR markers and efficiently demarcated the lessThan i greaterThan O.basilicum Linn. var. pilosum (willd)- Benth lessThan /i greaterThan from other lessThan i greaterThan Ocimum lessThan /i greaterThan varieties. lessThan i greaterThan The lessThan /i greaterThan leaf extract of lessThan i greaterThan O.basilicum Linn. var. pilosum (willd)- Benth lessThan /i greaterThan was analyzed by GC-MS and 15 compounds were identified. Compounds which are structurally similar to the DEET were docked with Schrodinger mastero software. n-Hexa decanoic acid and , 4H-1-Benzopyran-4-One,5-Hydroxy-6,7-Dimethoxy-2-(4-Methoxyphenyl) were shown good docking scores with mosquito odorant binding protein 3N7H. N-Hexa decanoic acid present in lessThan i greaterThan O.basilicum Linn. var. pilosum (willd)- Benth lessThan /i greaterThan found to be an ideal candidate for development of another potential mosquito repellent.
VENU GOPAL GADDAGUTI, REPALLE SREE DEEPTHI AND ALLU PRASADA RAO
EST SSR, Molecular Docking, O.basilicum Linn. var. pilosum (willd)- Benth
437-445