International Journal of Pharma and Bio Sciences
ijpbs.net
editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 4 Issue 2
2013 (April - June)
DENDRIMER APPLICATIONS – A REVIEW
As a new class of a synthetic polymers based on a well-defined cascade macromolecules synthesized to reach various demands in the field of electrical, chemical, biological, medicinal and biotechnology. Dendrimers have proved themselves to be very challenging and applicative; as the structure provides high degree of surface functionality, versatility and the unique properties like uniform size, high degree of branching, multivalency, water solubility, well defined molecular weight and also the available internal cavities. The ability of this macromolecule to construct a definite architectural design of dendrimers with respect to size and shape, length of branching, density, and its well defined molecular structure and segmented spherical construction has opened a wide area of research by understanding the interactions taking place between the biological entities. This review cover a few basic information of dendrimers and much about their possible applications in various areas such as biomedical field, as imaging contrast agents, therapeutic agent, diagnostic agent, gene transfection, drug delivery, targeted drug delivery, solubility enhancer, light harvesting, catalyst, additives, printing ink, paints, biomimics, and many other areas of science. The impact of dendrimer applications on biomedical field as demonstrated in this review; shows major potential and high hopes for the future of dendrimers.
H.N.PATEL AND DR. P.M.PATEL
Dendrimer, Drug carriers, PAMAM, Dendritic polymers.
454-463