International Journal of Pharma and Bio Sciences
ijpbs.net
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10.22376/ijpbs.2019.10.1.p1-12
Volume 3 Issue 2
2012 (April - June)
An Invitro Evaluation Of Cytotoxic Activity Of Sophora Interrupta
In this study we evaluated the cytotoxicity activity of Sophora interrupta. For evaluation HeLa and HePG2 cell lines were treated with the various concentrations of Methanolic extract. The result showed an IC lessThan sub greaterThan 50 lessThan /sub greaterThan value of 211.5µg/ml and158.2µg/ml respectively in HeLa and HePG2 cell lines. The MTT assay results confirmed the cytotoxicity of the plant. Further, molecular characterisation studies and in vivo studies recommended to confirm still the anticancer activity of this plant.
T. Vithya, Dr.V.Kavimani, K.Alhasjajiju, B.Rajkapoor And B.K.Savitha
Sophora interrupta, MTT assay, HeLa, HePG2, Cytotoxicity
420-425